2024
Health care disparities in morbidity and mortality in adults with acute and remote status epilepticus: A national study.
Tantillo GB, Dongarwar D, Venkatasubba Rao CP, Johnson A, Camey S, Reyes O, Baroni M, Kapur J, Salihu HM, Jetté N. Epilepsia. 2024 Apr 30. doi: 10.1111/epi.17965. Epub ahead of print. PMID: 38687128.
Which terms should be used to describe medications used in the treatment of seizure disorders?
Perucca E, French JA, Aljandeel G, Balestrini S, Braga P, Burneo JG, Felli AC, Cross JH, Galanopoulou AS, Jain S, Jiang Y, Kälviäinen R, Lim SH, Meador KJ, Mogal Z, Nabbout R, Sofia F, Somerville E, Sperling MR, Triki C, Trinka E, Walker MC, Wiebe S, Wilmshurst JM, Wirrell E, Yacubian EM, Kapur J. An ILAE position paper. Epilepsia. 2024 Mar;65(3):533-541. doi: 10.1111/epi.17877. Epub 2024 Jan 27. PMID: 38279786; PMCID: PMC10948296.
Anatomical Substrates of Rapid Eye Movement Sleep Rebound in a Rodent Model of Post-sevoflurane Sleep Disruption.
Atluri N, Dulko E, Jedrusiak M, Klos J, Osuru HP, Davis E, Beenhakker M, Kapur J, Zuo Z, Lunardi N. Anesthesiology. 2024 Apr 1;140(4):729-741. doi: 10.1097/ALN.0000000000004893. PMID: 38157434; PMCID: PMC10939895.
Memantine's double duty? Investigating its impact on epilepsy control in Alzheimer's disease.
Rayala H, Kapur J, El-Haija HA, Parikh P, Zawar I. Epileptic Disord. 2024 Apr;26(2):261-263. doi: 10.1002/epd2.20202. Epub 2024 Feb 9. PMID: 38334219.
Tantillo GB, Dongarwar D, Venkatasubba Rao CP, Johnson A, Camey S, Reyes O, Baroni M, Kapur J, Salihu HM, Jetté N. Epilepsia. 2024 Apr 30. doi: 10.1111/epi.17965. Epub ahead of print. PMID: 38687128.
Which terms should be used to describe medications used in the treatment of seizure disorders?
Perucca E, French JA, Aljandeel G, Balestrini S, Braga P, Burneo JG, Felli AC, Cross JH, Galanopoulou AS, Jain S, Jiang Y, Kälviäinen R, Lim SH, Meador KJ, Mogal Z, Nabbout R, Sofia F, Somerville E, Sperling MR, Triki C, Trinka E, Walker MC, Wiebe S, Wilmshurst JM, Wirrell E, Yacubian EM, Kapur J. An ILAE position paper. Epilepsia. 2024 Mar;65(3):533-541. doi: 10.1111/epi.17877. Epub 2024 Jan 27. PMID: 38279786; PMCID: PMC10948296.
Anatomical Substrates of Rapid Eye Movement Sleep Rebound in a Rodent Model of Post-sevoflurane Sleep Disruption.
Atluri N, Dulko E, Jedrusiak M, Klos J, Osuru HP, Davis E, Beenhakker M, Kapur J, Zuo Z, Lunardi N. Anesthesiology. 2024 Apr 1;140(4):729-741. doi: 10.1097/ALN.0000000000004893. PMID: 38157434; PMCID: PMC10939895.
Memantine's double duty? Investigating its impact on epilepsy control in Alzheimer's disease.
Rayala H, Kapur J, El-Haija HA, Parikh P, Zawar I. Epileptic Disord. 2024 Apr;26(2):261-263. doi: 10.1002/epd2.20202. Epub 2024 Feb 9. PMID: 38334219.
2023
Neuronal plasticity contributes to postictal death.
Brodovskaya A, Sun H, Adotevi N, Wenker IC, Mitchell KE, Clements RT, Kapur J. Prog Neurobiol. 2023 Sep 29;231:102531. doi: 10.1016/j.pneurobio.2023.102531. Epub ahead of print. PMID: 37778436.
Progesterone Receptor Activation Regulates Sensory Sensitivity and Migraine Susceptibility.
Joshi S, Williamson J, Moosa S, Kapur J.J Pain. 2023 Sep 28:S1526-5900(23)00546-1. doi: 10.1016/j.jpain.2023.09.017. Epub ahead of print. PMID: 37777034.
Glycolytic lactate production supports status epilepticus in experimental animals.
Skwarzynska D, Sun H, Kasprzak I, Sharma S, Williamson J, Kapur J. Ann Clin Transl Neurol. 2023 Oct;10(10):1873-1884. doi: 10.1002/acn3.51881. Epub 2023 Aug 25. PMID: 37632130; PMCID: PMC10578888.
Desirability of Outcome Ranking for Status Epilepticus: A Benefit-Risk Approach to Design and Analyses of Clinical SE Trials.
Chamberlain JM, Kapur J, Silbergleit RS, Elm JJ, Rosenthal ES, Bleck TP, Shinnar S, Zetabchi S, Evans SR. Neurology. 2023 Oct 17;101(16):e1633-e1639. doi: 10.1212/WNL.0000000000207684. Epub 2023 Aug 14. PMID: 37580166; PMCID: PMC10585669.
Drug-Inducible Gene Therapy Effectively Reduces Spontaneous Seizures in Kindled Rats but Creates Off-Target Side Effects in Inhibitory Neurons.
Sullivan KA, Vitko I, Blair K, Gaykema RP, Failor MJ, San Pietro JM, Dey D, Williamson JM, Stornetta RL, Kapur J, Perez-Reyes E. Int J Mol Sci. 2023 Jul 12;24(14):11347. doi: 10.3390/ijms241411347. PMID: 37511107; PMCID: PMC10379297.
Connectivity and Excitability Shape Seizure Circuits.
Brodovskaya A, Kapur J. Epilepsy Curr. 2022 Nov 28;23(3):169-174. doi: 10.1177/15357597221136961. PMID: 37334420; PMCID: PMC10273819.
Does Alzheimer's disease with mesial temporal lobe epilepsy represent a distinct disease subtype?
Zawar I, Kapur J. Alzheimers Dement. 2023 Jun;19(6):2697-2706. doi: 10.1002/alz.12943. PMID: 36648207
Glycolysis regulates neuronal excitability via lactate receptor, HCA1R.
Skwarzynska D, Sun H, Williamson J, Kasprzak I, Kapur J. Brain. 2023 May 2;146(5):1888-1902. doi: 10.1093/brain/awac419. PMID: 36346130
Increased glutamatergic synaptic transmission during development in layer II/III mouse motor cortex pyramidal neurons.
Burnsed J, Matysik W, Yang L, Sun H, Joshi S, Kapur J. Cereb Cortex. 2023 Apr 4;33(8):4645-4653. doi: 10.1093/cercor/bhac368. PMID: 36137566
Measuring vagal activity in postictal bradycardia.
Schomer AC, Baljak V, Lynch M, Clark M, Kapur J. Epilepsy Behav. 2023 Apr;141:109148. doi: 10.1016/j.yebeh.2023.109148. PMID: 36907083
Why ketamine. Coles L, Rosenthal ES, Bleck TP, Elm J, Zehtabchi S, Chamberlain J, Cloyd J, Shinnar S, Silbergleit R, Kapur J. Epilepsy Behav. 2023 Apr;141:109066. doi: 10.1016/j.yebeh.2022.109066. PMID: 36609129
Limbic progesterone receptors regulate spatial memory.
Joshi S, Williams CL, Kapur J. Sci Rep. 2023 Feb 7;13(1):2164. doi: 10.1038/s41598-023-29100-2. PMID: 36750584
An Expected Score Approach to Ordinal Outcomes in a Bayesian, Response Adaptive, Randomized Trial.
Beall J, Elm J, Chamberlain J, Rosenthal E, Kapur J, Durkalski-Mauldin V. Stat Biopharm Res. 2023;15(4):820-825. doi: 10.1080/19466315.2023.2169344. Epub 2023 Feb 24. PMID: 38361772; PMCID: PMC10869112.
Brodovskaya A, Sun H, Adotevi N, Wenker IC, Mitchell KE, Clements RT, Kapur J. Prog Neurobiol. 2023 Sep 29;231:102531. doi: 10.1016/j.pneurobio.2023.102531. Epub ahead of print. PMID: 37778436.
Progesterone Receptor Activation Regulates Sensory Sensitivity and Migraine Susceptibility.
Joshi S, Williamson J, Moosa S, Kapur J.J Pain. 2023 Sep 28:S1526-5900(23)00546-1. doi: 10.1016/j.jpain.2023.09.017. Epub ahead of print. PMID: 37777034.
Glycolytic lactate production supports status epilepticus in experimental animals.
Skwarzynska D, Sun H, Kasprzak I, Sharma S, Williamson J, Kapur J. Ann Clin Transl Neurol. 2023 Oct;10(10):1873-1884. doi: 10.1002/acn3.51881. Epub 2023 Aug 25. PMID: 37632130; PMCID: PMC10578888.
Desirability of Outcome Ranking for Status Epilepticus: A Benefit-Risk Approach to Design and Analyses of Clinical SE Trials.
Chamberlain JM, Kapur J, Silbergleit RS, Elm JJ, Rosenthal ES, Bleck TP, Shinnar S, Zetabchi S, Evans SR. Neurology. 2023 Oct 17;101(16):e1633-e1639. doi: 10.1212/WNL.0000000000207684. Epub 2023 Aug 14. PMID: 37580166; PMCID: PMC10585669.
Drug-Inducible Gene Therapy Effectively Reduces Spontaneous Seizures in Kindled Rats but Creates Off-Target Side Effects in Inhibitory Neurons.
Sullivan KA, Vitko I, Blair K, Gaykema RP, Failor MJ, San Pietro JM, Dey D, Williamson JM, Stornetta RL, Kapur J, Perez-Reyes E. Int J Mol Sci. 2023 Jul 12;24(14):11347. doi: 10.3390/ijms241411347. PMID: 37511107; PMCID: PMC10379297.
Connectivity and Excitability Shape Seizure Circuits.
Brodovskaya A, Kapur J. Epilepsy Curr. 2022 Nov 28;23(3):169-174. doi: 10.1177/15357597221136961. PMID: 37334420; PMCID: PMC10273819.
Does Alzheimer's disease with mesial temporal lobe epilepsy represent a distinct disease subtype?
Zawar I, Kapur J. Alzheimers Dement. 2023 Jun;19(6):2697-2706. doi: 10.1002/alz.12943. PMID: 36648207
Glycolysis regulates neuronal excitability via lactate receptor, HCA1R.
Skwarzynska D, Sun H, Williamson J, Kasprzak I, Kapur J. Brain. 2023 May 2;146(5):1888-1902. doi: 10.1093/brain/awac419. PMID: 36346130
Increased glutamatergic synaptic transmission during development in layer II/III mouse motor cortex pyramidal neurons.
Burnsed J, Matysik W, Yang L, Sun H, Joshi S, Kapur J. Cereb Cortex. 2023 Apr 4;33(8):4645-4653. doi: 10.1093/cercor/bhac368. PMID: 36137566
Measuring vagal activity in postictal bradycardia.
Schomer AC, Baljak V, Lynch M, Clark M, Kapur J. Epilepsy Behav. 2023 Apr;141:109148. doi: 10.1016/j.yebeh.2023.109148. PMID: 36907083
Why ketamine. Coles L, Rosenthal ES, Bleck TP, Elm J, Zehtabchi S, Chamberlain J, Cloyd J, Shinnar S, Silbergleit R, Kapur J. Epilepsy Behav. 2023 Apr;141:109066. doi: 10.1016/j.yebeh.2022.109066. PMID: 36609129
Limbic progesterone receptors regulate spatial memory.
Joshi S, Williams CL, Kapur J. Sci Rep. 2023 Feb 7;13(1):2164. doi: 10.1038/s41598-023-29100-2. PMID: 36750584
An Expected Score Approach to Ordinal Outcomes in a Bayesian, Response Adaptive, Randomized Trial.
Beall J, Elm J, Chamberlain J, Rosenthal E, Kapur J, Durkalski-Mauldin V. Stat Biopharm Res. 2023;15(4):820-825. doi: 10.1080/19466315.2023.2169344. Epub 2023 Feb 24. PMID: 38361772; PMCID: PMC10869112.
2022
Chronic neuronal activation leads to elevated lactate dehydrogenase A through the AMP-activated protein kinase/hypoxia-inducible factor-1α hypoxia pathway.
Ksendzovsky A, Bachani M, Altshuler M, Walbridge S, Mortazavi A, Moyer M, Chen C, Fayed I, Steiner J, Edwards N, Inati SK, Jahanipour J, Maric D, Heiss JD, Kapur J, Zaghloul KA. Brain Commun. 2022 Dec 1;5(1):fcac298. doi: 10.1093/braincomms/fcac298. PMID: 36655171
Connectivity and excitability shape seizure circuits.
Brodovskaya A, Kapur J. Epilepsy Curr. 2022 Nov 28;23(3):169-174. doi: 10.1177/15357597221136961. PMID: 37334420
Consequences: Bench to home.
Kapur J, Long L, Dixon-Salazar T. Epilepsia. 2022 Sep;63 Suppl 1:S14-S24. doi: 10.1111/epi.17342. PMID: 35999173
Treatment of toxin-related status epilepticus with levetiracetam, fosphenytoin, or valproate in patients enrolled in the established status epilepticus treatment trial.
Coralic Z, Kapur J, Olson KR, Chamberlain JM, Overbeek D, Silbergleit R. Ann Emerg Med. 2022 Sep;80(3):194-202. doi: 10.1016/j.annemergmed.2022.04.020. PMID: 35718575
Electroencephalographic seizures in emergency department patients after treatment for convulsive status epilepticus.
Zehtabchi S, Silbergleit R, Chamberlain JM, Shinnar S, Elm JJ, Underwood E, Rosenthal ES, Bleck TP, Kapur J. J Clin Neurophysiol. 2022 Sep 1;39(6):441-445. doi: 10.1097/WNP.0000000000000800. PMID: 33337664
Extrahippocampal seizure and memory circuits overlap.
Naik AA, Brodovskaya A, Subedi S, Akram A, Kapur J. eNeuro. 2022 Jul 18;9(4):ENEURO.0179-22.2022. doi: 10.1523/ENEURO.0179-22.2022. PMID: 35853724
Distinct roles of rodent thalamus and corpus callosum in seizure generalization.
Brodovskaya A, Batabyal T, Shiono S, Sun H, Kapur J. Ann Neurol. 2022 May;91(5):682-696. doi: 10.1002/ana.26338. PMID: 35226367
Neuronal circuits sustaining neocortical-injury-induced status epilepticus.
Singh T, Batabyal T, Kapur J. Neurobiol Dis. 2022 Apr;165:105633. doi: 10.1016/j.nbd.2022.105633. PMID: 35065250
Construction of local field potential microelectrodes for in vivo recordings from multiple brain structures simultaneously.
Brodovskaya A, Shiono S, Batabyal T, Williamson J, Kapur J. J Vis Exp. 2022 Mar 14;(181). doi: 10.3791/63633. PMID: 35343955
Focal impaired awareness seizures in a rodent model: A functional anatomy.
Adotevi N, Kapur J. Epilepsia Open. 2022 Mar;7(1):110-123. doi: 10.1002/epi4.12563. PMID: 34822222
Efficient learning of transform-domain LMS filter using graph laplacian.
Batabyal T, Weller D, Kapur J, Acton ST. IEEE Trans Neural Netw Learn Syst. 2022 Feb 4;PP:10.1109/TNNLS.2022.3144637. doi: 10.1109/TNNLS.2022.3144637. PMID: 35120011
Ksendzovsky A, Bachani M, Altshuler M, Walbridge S, Mortazavi A, Moyer M, Chen C, Fayed I, Steiner J, Edwards N, Inati SK, Jahanipour J, Maric D, Heiss JD, Kapur J, Zaghloul KA. Brain Commun. 2022 Dec 1;5(1):fcac298. doi: 10.1093/braincomms/fcac298. PMID: 36655171
Connectivity and excitability shape seizure circuits.
Brodovskaya A, Kapur J. Epilepsy Curr. 2022 Nov 28;23(3):169-174. doi: 10.1177/15357597221136961. PMID: 37334420
Consequences: Bench to home.
Kapur J, Long L, Dixon-Salazar T. Epilepsia. 2022 Sep;63 Suppl 1:S14-S24. doi: 10.1111/epi.17342. PMID: 35999173
Treatment of toxin-related status epilepticus with levetiracetam, fosphenytoin, or valproate in patients enrolled in the established status epilepticus treatment trial.
Coralic Z, Kapur J, Olson KR, Chamberlain JM, Overbeek D, Silbergleit R. Ann Emerg Med. 2022 Sep;80(3):194-202. doi: 10.1016/j.annemergmed.2022.04.020. PMID: 35718575
Electroencephalographic seizures in emergency department patients after treatment for convulsive status epilepticus.
Zehtabchi S, Silbergleit R, Chamberlain JM, Shinnar S, Elm JJ, Underwood E, Rosenthal ES, Bleck TP, Kapur J. J Clin Neurophysiol. 2022 Sep 1;39(6):441-445. doi: 10.1097/WNP.0000000000000800. PMID: 33337664
Extrahippocampal seizure and memory circuits overlap.
Naik AA, Brodovskaya A, Subedi S, Akram A, Kapur J. eNeuro. 2022 Jul 18;9(4):ENEURO.0179-22.2022. doi: 10.1523/ENEURO.0179-22.2022. PMID: 35853724
Distinct roles of rodent thalamus and corpus callosum in seizure generalization.
Brodovskaya A, Batabyal T, Shiono S, Sun H, Kapur J. Ann Neurol. 2022 May;91(5):682-696. doi: 10.1002/ana.26338. PMID: 35226367
Neuronal circuits sustaining neocortical-injury-induced status epilepticus.
Singh T, Batabyal T, Kapur J. Neurobiol Dis. 2022 Apr;165:105633. doi: 10.1016/j.nbd.2022.105633. PMID: 35065250
Construction of local field potential microelectrodes for in vivo recordings from multiple brain structures simultaneously.
Brodovskaya A, Shiono S, Batabyal T, Williamson J, Kapur J. J Vis Exp. 2022 Mar 14;(181). doi: 10.3791/63633. PMID: 35343955
Focal impaired awareness seizures in a rodent model: A functional anatomy.
Adotevi N, Kapur J. Epilepsia Open. 2022 Mar;7(1):110-123. doi: 10.1002/epi4.12563. PMID: 34822222
Efficient learning of transform-domain LMS filter using graph laplacian.
Batabyal T, Weller D, Kapur J, Acton ST. IEEE Trans Neural Netw Learn Syst. 2022 Feb 4;PP:10.1109/TNNLS.2022.3144637. doi: 10.1109/TNNLS.2022.3144637. PMID: 35120011
2021
Connectivity and neuronal synchrony during seizures.
Ren X, Brodovskaya A, Hudson JL, Kapur J. J Neurosci. 2021 Sep 8;41(36):7623-7635. doi: 10.1523/JNEUROSCI.0669-21.2021. PMID: 34326143
Anticonvulsant dopamine type 2 receptor agonist activates inhibitory parvalbumin interneurons.
Brodovskaya A, Kapur J. Epilepsia. 2021 Sep;62(9):e147-e152. doi: 10.1111/epi.17004. PMID: 34331457
Activation of the basal ganglia and indirect pathway neurons during frontal lobe seizures.
Brodovskaya A, Shiono S, Kapur J. Brain. 2021 Aug 17;144(7):2074-2091. doi: 10.1093/brain/awab119. PMID: 33730155
Limbic progesterone receptor activity enhances neuronal excitability and seizures.
Shiono S, Sun H, Batabyal T, Labuz A, Williamson J, Kapur J, Joshi S. Epilepsia. 2021 Aug;62(8):1946-1959. doi: 10.1111/epi.16970. PMID: 34164810
A pharmacokinetic simulation study to assess the performance of a sparse blood sampling approach to quantify early drug exposure.
Sathe AG, Brundage RC, Ivaturi V, Cloyd JC, Chamberlain JM, Elm JJ, Silbergleit R, Kapur J, Coles LD. Clin Transl Sci. 2021 Jul;14(4):1444-1451. doi: 10.1111/cts.13004. PMID: 33742783
Early exposure of fosphenytoin, levetiracetam, and valproic acid after high-dose intravenous administration in young children with benzodiazepine-refractory status epilepticus.
Sathe AG, Mishra U, Ivaturi V, Brundage RC, Cloyd JC, Elm JJ, Chamberlain JM, Silbergleit R, Kapur J, Lowenstein DH, Shinnar S, Cock HR, Fountain NB, Babcock L, Coles LD. J Clin Pharmacol. 2021 Jun;61(6):763-768. doi: 10.1002/jcph.1801. PMID: 33336359
Early neurologic recovery, practice pattern variation, and the risk of endotracheal intubation following established status epilepticus.
Rosenthal ES, Elm JJ, Ingles J, Rogers AJ, Terndrup TE, Holsti M, Thomas DG, Babcock L, Okada PJ, Lipsky RH, Miller JB, Hickey RW, Barra ME, Bleck TP, Cloyd JC, Silbergleit R, Lowenstein DH, Coles LD, Kapur J, Shinnar S, Chamberlain JM; Established Status Epilepticus Treatment Trial Study Group. Neurology. 2021 May 11;96(19):e2372-e2386. doi: 10.1212/WNL.0000000000011879. PMID: 34032604
Synergistic effect of sleep depth and seizures correlates with postictal heart rate.
Schomer AC, Lynch M, Lowenhaupt S, Leonardo J, Baljak V, Clark M, Kapur J, Quigg M. Epilepsia. 2021 May;62(5):e65-e69. doi: 10.1111/epi.16869. PMID: 33713433
Mechanism of seizure-induced retrograde amnesia.
Naik AA, Sun H, Williams CL, Weller DS, Julius Zhu J, Kapur J. Prog Neurobiol. 2021 May;200:101984. doi: 10.1016/j.pneurobio.2020.101984. PMID: 33388373
Patterns of benzodiazepine underdosing in the Established Status Epilepticus Treatment Trial.
Sathe AG, Underwood E, Coles LD, Elm JJ, Silbergleit R, Chamberlain JM, Kapur J, Cock HR, Fountain NB, Shinnar S, Lowenstein DH, Rosenthal ES, Conwit RA, Bleck TP, Cloyd JC. Epilepsia. 2021 Mar;62(3):795-806. doi: 10.1111/epi.16825. PMID: 33567109
Improvement in Symptomatic Gastroparesis With Increased Vagal Nerve Stimulation.
Dougherty MI, Zarroli K, Kapur J. Neurol Clin Pract. 2021 Feb;11(1):e18-e19. doi: 10.1212/CPJ.0000000000000775. PMID: 33968483
Progesterone modulates neuronal excitability bidirectionally.
Kapur J, Joshi S. Neurosci Lett. 2021 Jan 23;744:135619. doi: 10.1016/j.neulet.2020.135619. PMID: 33421486
Difluoroboron β-diketonate polylactic acid oxygen nanosensors for intracellular neuronal imaging.
Zhuang M, Joshi S, Sun H, Batabyal T, Fraser CL, Kapur J. Sci Rep. 2021 Jan 13;11(1):1076. doi: 10.1038/s41598-020-80172-w. PMID: 33441771
Ren X, Brodovskaya A, Hudson JL, Kapur J. J Neurosci. 2021 Sep 8;41(36):7623-7635. doi: 10.1523/JNEUROSCI.0669-21.2021. PMID: 34326143
Anticonvulsant dopamine type 2 receptor agonist activates inhibitory parvalbumin interneurons.
Brodovskaya A, Kapur J. Epilepsia. 2021 Sep;62(9):e147-e152. doi: 10.1111/epi.17004. PMID: 34331457
Activation of the basal ganglia and indirect pathway neurons during frontal lobe seizures.
Brodovskaya A, Shiono S, Kapur J. Brain. 2021 Aug 17;144(7):2074-2091. doi: 10.1093/brain/awab119. PMID: 33730155
Limbic progesterone receptor activity enhances neuronal excitability and seizures.
Shiono S, Sun H, Batabyal T, Labuz A, Williamson J, Kapur J, Joshi S. Epilepsia. 2021 Aug;62(8):1946-1959. doi: 10.1111/epi.16970. PMID: 34164810
A pharmacokinetic simulation study to assess the performance of a sparse blood sampling approach to quantify early drug exposure.
Sathe AG, Brundage RC, Ivaturi V, Cloyd JC, Chamberlain JM, Elm JJ, Silbergleit R, Kapur J, Coles LD. Clin Transl Sci. 2021 Jul;14(4):1444-1451. doi: 10.1111/cts.13004. PMID: 33742783
Early exposure of fosphenytoin, levetiracetam, and valproic acid after high-dose intravenous administration in young children with benzodiazepine-refractory status epilepticus.
Sathe AG, Mishra U, Ivaturi V, Brundage RC, Cloyd JC, Elm JJ, Chamberlain JM, Silbergleit R, Kapur J, Lowenstein DH, Shinnar S, Cock HR, Fountain NB, Babcock L, Coles LD. J Clin Pharmacol. 2021 Jun;61(6):763-768. doi: 10.1002/jcph.1801. PMID: 33336359
Early neurologic recovery, practice pattern variation, and the risk of endotracheal intubation following established status epilepticus.
Rosenthal ES, Elm JJ, Ingles J, Rogers AJ, Terndrup TE, Holsti M, Thomas DG, Babcock L, Okada PJ, Lipsky RH, Miller JB, Hickey RW, Barra ME, Bleck TP, Cloyd JC, Silbergleit R, Lowenstein DH, Coles LD, Kapur J, Shinnar S, Chamberlain JM; Established Status Epilepticus Treatment Trial Study Group. Neurology. 2021 May 11;96(19):e2372-e2386. doi: 10.1212/WNL.0000000000011879. PMID: 34032604
Synergistic effect of sleep depth and seizures correlates with postictal heart rate.
Schomer AC, Lynch M, Lowenhaupt S, Leonardo J, Baljak V, Clark M, Kapur J, Quigg M. Epilepsia. 2021 May;62(5):e65-e69. doi: 10.1111/epi.16869. PMID: 33713433
Mechanism of seizure-induced retrograde amnesia.
Naik AA, Sun H, Williams CL, Weller DS, Julius Zhu J, Kapur J. Prog Neurobiol. 2021 May;200:101984. doi: 10.1016/j.pneurobio.2020.101984. PMID: 33388373
Patterns of benzodiazepine underdosing in the Established Status Epilepticus Treatment Trial.
Sathe AG, Underwood E, Coles LD, Elm JJ, Silbergleit R, Chamberlain JM, Kapur J, Cock HR, Fountain NB, Shinnar S, Lowenstein DH, Rosenthal ES, Conwit RA, Bleck TP, Cloyd JC. Epilepsia. 2021 Mar;62(3):795-806. doi: 10.1111/epi.16825. PMID: 33567109
Improvement in Symptomatic Gastroparesis With Increased Vagal Nerve Stimulation.
Dougherty MI, Zarroli K, Kapur J. Neurol Clin Pract. 2021 Feb;11(1):e18-e19. doi: 10.1212/CPJ.0000000000000775. PMID: 33968483
Progesterone modulates neuronal excitability bidirectionally.
Kapur J, Joshi S. Neurosci Lett. 2021 Jan 23;744:135619. doi: 10.1016/j.neulet.2020.135619. PMID: 33421486
Difluoroboron β-diketonate polylactic acid oxygen nanosensors for intracellular neuronal imaging.
Zhuang M, Joshi S, Sun H, Batabyal T, Fraser CL, Kapur J. Sci Rep. 2021 Jan 13;11(1):1076. doi: 10.1038/s41598-020-80172-w. PMID: 33441771
2020
Neocortical injury-induced status epilepticus.Singh T, Joshi S, Williamson JM, Kapur J. Epilepsia. 2020 Dec;61(12):2811-2824. doi: 10.1111/epi.16715. PMID: 33063874
Characterization of kindled VGAT-Cre mice as a new animal model of temporal lobe epilepsy.
Straub J, Gawda A, Ravichandran P, McGrew B, Nylund E, Kang J, Burke C, Vitko I, Scott M, Williamson J, Joshi S, Kapur J, Perez-Reyes E. Epilepsia. 2020 Oct;61(10):2277-2288. doi: 10.1111/epi.16651. PMID: 32954490
Continuous video electroencephalogram during hypoxia-ischemia in neonatal mice.
Wagley PK, Williamson J, Skwarzynska D, Kapur J, Burnsed J. J Vis Exp. 2020 Jun 11;(160):10.3791/61346. doi: 10.3791/61346. PMID: 32597865
The association of patient weight and dose of fosphenytoin, levetiracetam, and valproic acid with treatment success in status epilepticus.
Sathe AG, Elm JJ, Cloyd JC, Chamberlain JM, Silbergleit R, Kapur J, Cock HR, Fountain NB, Shinnar S, Lowenstein DH, Conwit RA, Bleck TP, Coles LD. Epilepsia. 2020 Jun;61(6):e66-e70. doi: 10.1111/epi.16534. PMID: 32420641
Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial.
Chamberlain JM, Kapur J, Shinnar S, Elm J, Holsti M, Babcock L, Rogers A, Barsan W, Cloyd J, Lowenstein D, Bleck TP, Conwit R, Meinzer C, Cock H, Fountain NB, Underwood E, Connor JT, Silbergleit R; Neurological Emergencies Treatment Trials; Pediatric Emergency Care Applied Research Network investigators. Lancet. 2020 Apr 11;395(10231):1217-1224. doi: 10.1016/S0140-6736(20)30611-5. PMID: 32203691
Reduced neurosteroid potentiation of GABAA receptors in epilepsy and depolarized hippocampal neurons.
Joshi S, Roden WH, Kapur J, Jansen LA. Ann Clin Transl Neurol. 2020 Apr;7(4):527-542. doi: 10.1002/acn3.51023. PMID: 32243088
α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor plasticity sustains severe, fatal status epilepticus.
Adotevi N, Lewczuk E, Sun H, Joshi S, Dabrowska N, Shan S, Williamson J, Kapur J. Ann Neurol. 2020 Jan;87(1):84-96. doi: 10.1002/ana.25635. PMID: 31675128
Characterization of kindled VGAT-Cre mice as a new animal model of temporal lobe epilepsy.
Straub J, Gawda A, Ravichandran P, McGrew B, Nylund E, Kang J, Burke C, Vitko I, Scott M, Williamson J, Joshi S, Kapur J, Perez-Reyes E. Epilepsia. 2020 Oct;61(10):2277-2288. doi: 10.1111/epi.16651. PMID: 32954490
Continuous video electroencephalogram during hypoxia-ischemia in neonatal mice.
Wagley PK, Williamson J, Skwarzynska D, Kapur J, Burnsed J. J Vis Exp. 2020 Jun 11;(160):10.3791/61346. doi: 10.3791/61346. PMID: 32597865
The association of patient weight and dose of fosphenytoin, levetiracetam, and valproic acid with treatment success in status epilepticus.
Sathe AG, Elm JJ, Cloyd JC, Chamberlain JM, Silbergleit R, Kapur J, Cock HR, Fountain NB, Shinnar S, Lowenstein DH, Conwit RA, Bleck TP, Coles LD. Epilepsia. 2020 Jun;61(6):e66-e70. doi: 10.1111/epi.16534. PMID: 32420641
Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial.
Chamberlain JM, Kapur J, Shinnar S, Elm J, Holsti M, Babcock L, Rogers A, Barsan W, Cloyd J, Lowenstein D, Bleck TP, Conwit R, Meinzer C, Cock H, Fountain NB, Underwood E, Connor JT, Silbergleit R; Neurological Emergencies Treatment Trials; Pediatric Emergency Care Applied Research Network investigators. Lancet. 2020 Apr 11;395(10231):1217-1224. doi: 10.1016/S0140-6736(20)30611-5. PMID: 32203691
Reduced neurosteroid potentiation of GABAA receptors in epilepsy and depolarized hippocampal neurons.
Joshi S, Roden WH, Kapur J, Jansen LA. Ann Clin Transl Neurol. 2020 Apr;7(4):527-542. doi: 10.1002/acn3.51023. PMID: 32243088
α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor plasticity sustains severe, fatal status epilepticus.
Adotevi N, Lewczuk E, Sun H, Joshi S, Dabrowska N, Shan S, Williamson J, Kapur J. Ann Neurol. 2020 Jan;87(1):84-96. doi: 10.1002/ana.25635. PMID: 31675128
2019
Lessons from the Established Status Epilepticus Treatment Trial.
Cock HR, Coles LD, Elm J, Silbergleit R, Chamberlain JM, Cloyd JC, Fountain N, Shinnar S, Lowenstein D, Conwit R, Bleck TP, Kapur J. Epilepsy Behav. 2019 Dec;101(Pt B):106296. doi: 10.1016/j.yebeh.2019.04.049. PMID: 31653603
Neuronal circuit activity during neonatal hypoxic-ischemic seizures in mice.
Burnsed J, Skwarzyńska D, Wagley PK, Isbell L, Kapur J. Ann Neurol. 2019 Dec;86(6):927-938. doi: 10.1002/ana.25601. PMID: 31509619
Circuits generating secondarily generalized seizures.
Brodovskaya A, Kapur J. Epilepsy Behav. 2019 Dec;101(Pt B):106474. doi: 10.1016/j.yebeh.2019.106474. PMID: 31431400
Neurobiology of organophosphate-induced seizures.
Williamson J, Singh T, Kapur J. Epilepsy Behav. 2019 Dec;101(Pt B):106426. doi: 10.1016/j.yebeh.2019.07.027. PMID: 31399343
Randomized trial of three anticonvulsant medications for status epilepticus.
Kapur J, Elm J, Chamberlain JM, Barsan W, Cloyd J, Lowenstein D, Shinnar S, Conwit R, Meinzer C, Cock H, Fountain N, Connor JT, Silbergleit R; NETT and PECARN Investigators. N Engl J Med. 2019 Nov 28;381(22):2103-2113. doi: 10.1056/NEJMoa1905795. PMID: 31774955
Parallel pathways of seizure generalization.
Dabrowska N, Joshi S, Williamson J, Lewczuk E, Lu Y, Oberoi S, Brodovskaya A, Kapur J. Brain. 2019 Aug 1;142(8):2336-2351. doi: 10.1093/brain/awz170. PMID: 31237945
Underdosing of benzodiazepines in patients with status epilepticus enrolled in Established Status Epilepticus Treatment Trial.
Sathe AG, Tillman H, Coles LD, Elm JJ, Silbergleit R, Chamberlain J, Kapur J, Cock HR, Fountain NB, Shinnar S, Lowenstein DH, Conwit RA, Bleck TP, Cloyd JC. Acad Emerg Med. 2019 Aug;26(8):940-943. doi: 10.1111/acem.13811. PMID: 31161706
Progesterone receptor activation regulates seizure susceptibility.
Shiono S, Williamson J, Kapur J, Joshi S. Ann Clin Transl Neurol. 2019 Jul;6(7):1302-1310. doi: 10.1002/acn3.50830. PMID: 31353848
WONOEP appraisal: Network concept from an imaging perspective.
Wykes RC, Khoo HM, Caciagli L, Blumenfeld H, Golshani P, Kapur J, Stern JM, Bernasconi A, Dedeurwaerdere S, Bernasconi N. Epilepsia. 2019 Jul;60(7):1293-1305. doi: 10.1111/epi.16067. PMID: 31179547
Structure-based intensity propagation for 3-D brain reconstruction with multilayer section microscopy.
Liang H, Dabrowska N, Kapur J, Weller DS. IEEE Trans Med Imaging. 2019 May;38(5):1106-1115. doi: 10.1109/TMI.2018.2878488. PMID: 30371359
Neurosteroid regulation of GABAA receptors: A role in catamenial epilepsy.
Joshi S, Kapur J. Brain Res. 2019 Jan 15;1703:31-40. doi: 10.1016/j.brainres.2018.02.031. PMID: 29481795
Cock HR, Coles LD, Elm J, Silbergleit R, Chamberlain JM, Cloyd JC, Fountain N, Shinnar S, Lowenstein D, Conwit R, Bleck TP, Kapur J. Epilepsy Behav. 2019 Dec;101(Pt B):106296. doi: 10.1016/j.yebeh.2019.04.049. PMID: 31653603
Neuronal circuit activity during neonatal hypoxic-ischemic seizures in mice.
Burnsed J, Skwarzyńska D, Wagley PK, Isbell L, Kapur J. Ann Neurol. 2019 Dec;86(6):927-938. doi: 10.1002/ana.25601. PMID: 31509619
Circuits generating secondarily generalized seizures.
Brodovskaya A, Kapur J. Epilepsy Behav. 2019 Dec;101(Pt B):106474. doi: 10.1016/j.yebeh.2019.106474. PMID: 31431400
Neurobiology of organophosphate-induced seizures.
Williamson J, Singh T, Kapur J. Epilepsy Behav. 2019 Dec;101(Pt B):106426. doi: 10.1016/j.yebeh.2019.07.027. PMID: 31399343
Randomized trial of three anticonvulsant medications for status epilepticus.
Kapur J, Elm J, Chamberlain JM, Barsan W, Cloyd J, Lowenstein D, Shinnar S, Conwit R, Meinzer C, Cock H, Fountain N, Connor JT, Silbergleit R; NETT and PECARN Investigators. N Engl J Med. 2019 Nov 28;381(22):2103-2113. doi: 10.1056/NEJMoa1905795. PMID: 31774955
Parallel pathways of seizure generalization.
Dabrowska N, Joshi S, Williamson J, Lewczuk E, Lu Y, Oberoi S, Brodovskaya A, Kapur J. Brain. 2019 Aug 1;142(8):2336-2351. doi: 10.1093/brain/awz170. PMID: 31237945
Underdosing of benzodiazepines in patients with status epilepticus enrolled in Established Status Epilepticus Treatment Trial.
Sathe AG, Tillman H, Coles LD, Elm JJ, Silbergleit R, Chamberlain J, Kapur J, Cock HR, Fountain NB, Shinnar S, Lowenstein DH, Conwit RA, Bleck TP, Cloyd JC. Acad Emerg Med. 2019 Aug;26(8):940-943. doi: 10.1111/acem.13811. PMID: 31161706
Progesterone receptor activation regulates seizure susceptibility.
Shiono S, Williamson J, Kapur J, Joshi S. Ann Clin Transl Neurol. 2019 Jul;6(7):1302-1310. doi: 10.1002/acn3.50830. PMID: 31353848
WONOEP appraisal: Network concept from an imaging perspective.
Wykes RC, Khoo HM, Caciagli L, Blumenfeld H, Golshani P, Kapur J, Stern JM, Bernasconi A, Dedeurwaerdere S, Bernasconi N. Epilepsia. 2019 Jul;60(7):1293-1305. doi: 10.1111/epi.16067. PMID: 31179547
Structure-based intensity propagation for 3-D brain reconstruction with multilayer section microscopy.
Liang H, Dabrowska N, Kapur J, Weller DS. IEEE Trans Med Imaging. 2019 May;38(5):1106-1115. doi: 10.1109/TMI.2018.2878488. PMID: 30371359
Neurosteroid regulation of GABAA receptors: A role in catamenial epilepsy.
Joshi S, Kapur J. Brain Res. 2019 Jan 15;1703:31-40. doi: 10.1016/j.brainres.2018.02.031. PMID: 29481795
2018
Role of NMDA receptors in the pathophysiology and treatment of status epilepticus.
Kapur J. Epilepsia Open. 2018 Nov 2;3(Suppl Suppl 2):165-168. doi: 10.1002/epi4.12270. PMID: 30564775
Mechanisms of status epilepticus: α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor hypothesis.Joshi S, Kapur J. Epilepsia. 2018 Oct;59 Suppl 2(Suppl 2):78-81. doi: 10.1111/epi.14482. PMID: 30159880
A novel therapeutic approach for treatment of catamenial epilepsy.
Joshi S, Sun H, Rajasekaran K, Williamson J, Perez-Reyes E, Kapur J. Neurobiol Dis. 2018 Mar;111:127-137. doi: 10.1016/j.nbd.2017.12.009. PMID: 29274741
Electroencephalography and behavior patterns during experimental status epilepticus.
Lewczuk E, Joshi S, Williamson J, Penmetsa M, Shan S, Kapur J. Epilepsia. 2018 Feb;59(2):369-380. doi: 10.1111/epi.13972. PMID: 29214651
Kapur J. Epilepsia Open. 2018 Nov 2;3(Suppl Suppl 2):165-168. doi: 10.1002/epi4.12270. PMID: 30564775
Mechanisms of status epilepticus: α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor hypothesis.Joshi S, Kapur J. Epilepsia. 2018 Oct;59 Suppl 2(Suppl 2):78-81. doi: 10.1111/epi.14482. PMID: 30159880
A novel therapeutic approach for treatment of catamenial epilepsy.
Joshi S, Sun H, Rajasekaran K, Williamson J, Perez-Reyes E, Kapur J. Neurobiol Dis. 2018 Mar;111:127-137. doi: 10.1016/j.nbd.2017.12.009. PMID: 29274741
Electroencephalography and behavior patterns during experimental status epilepticus.
Lewczuk E, Joshi S, Williamson J, Penmetsa M, Shan S, Kapur J. Epilepsia. 2018 Feb;59(2):369-380. doi: 10.1111/epi.13972. PMID: 29214651
2017
Flupirtine and diazepam combination terminates established status epilepticus: results in three rodent models.
Zhang T, Todorovic MS, Williamson J, Kapur J. Ann Clin Transl Neurol. 2017 Nov 7;4(12):888-896. doi: 10.1002/acn3.497. PMID: 29296617
Enhanced AMPA receptor-mediated neurotransmission on CA1 pyramidal neurons during status epilepticus.
Joshi S, Rajasekaran K, Sun H, Williamson J, Kapur J. Neurobiol Dis. 2017 Jul;103:45-53. doi: 10.1016/j.nbd.2017.03.017. PMID: 28377128
Isocitrate dehydrogenase mutations: A biomarker for glioma-related excitability and seizures.
Wychowski T, Kapur J. Neurology. 2017 May 9;88(19):1782-1783. doi: 10.1212/WNL.0000000000003922. PMID: 28404804
Gaining perspective on SUDEP: The new guideline.
Dworetzky BA, Kapur J. Neurology. 2017 Apr 25;88(17):1598-1599. doi: 10.1212/WNL.0000000000003698. PMID: 28438840
Neurosteroid-sensitive δ-GABAA receptors: A role in epileptogenesis?
Joshi S, Rajasekaran K, Williamson J, Kapur J. Epilepsia. 2017 Mar;58(3):494-504. doi: 10.1111/epi.13660. PMID: 28452419
Zhang T, Todorovic MS, Williamson J, Kapur J. Ann Clin Transl Neurol. 2017 Nov 7;4(12):888-896. doi: 10.1002/acn3.497. PMID: 29296617
Enhanced AMPA receptor-mediated neurotransmission on CA1 pyramidal neurons during status epilepticus.
Joshi S, Rajasekaran K, Sun H, Williamson J, Kapur J. Neurobiol Dis. 2017 Jul;103:45-53. doi: 10.1016/j.nbd.2017.03.017. PMID: 28377128
Isocitrate dehydrogenase mutations: A biomarker for glioma-related excitability and seizures.
Wychowski T, Kapur J. Neurology. 2017 May 9;88(19):1782-1783. doi: 10.1212/WNL.0000000000003922. PMID: 28404804
Gaining perspective on SUDEP: The new guideline.
Dworetzky BA, Kapur J. Neurology. 2017 Apr 25;88(17):1598-1599. doi: 10.1212/WNL.0000000000003698. PMID: 28438840
Neurosteroid-sensitive δ-GABAA receptors: A role in epileptogenesis?
Joshi S, Rajasekaran K, Williamson J, Kapur J. Epilepsia. 2017 Mar;58(3):494-504. doi: 10.1111/epi.13660. PMID: 28452419
